Family name Santillan Cruz (Santillan Cruz 
) , across the world, is a very rare surname. The family name Santillan Cruz is habitual in Latin America and the Caribbean, particularly Ecuador, where it is a rare surname, Peru, where it is an extremely rare surname, and Mexico.
| VARIANT | COUNTRY |
|---|---|
| Santillan Cruz | Mexico, Peru, United States, Ecuador |
Laura, and Jennifer Katherine